IONIS PHARMACEUTICALS INC

NASDAQ: IONS (Ionis Pharmaceuticals, Inc.)

最近更新时间: 2天之前, 1:32PM

81.68

-0.13 (-0.16%)

前收盘价格 81.81
收盘价格 82.19
成交量 1,714,986
平均成交量 (3个月) 2,475,015
市值 13,230,068,736
预期市盈率 (P/E Forward) 90.91
价格/销量 (P/S) 13.47
股市价格/股市净资产 (P/B) 21.49
52周波幅
23.95 (-70%) — 83.61 (2%)
利润日期 29 Oct 2025
营业毛利率 -63.86%
营业利益率 (TTM) -111.59%
稀释每股收益 (EPS TTM) -2.99
季度收入增长率 (YOY) 10.10%
总债务/股东权益 (D/E MRQ) 413.80%
流动比率 (MRQ) 9.66
营业现金流 (OCF TTM) -501.78 M
杠杆自由现金流 (LFCF TTM) -368.16 M
资产报酬率 (ROA TTM) -10.59%
股东权益报酬率 (ROE TTM) -118.62%

市场趋势

短期 中期
行业 Biotechnology (US) 混合的 混合的
Biotechnology (全球的) 混合的 混合的
股票 Ionis Pharmaceuticals, Inc. 看涨 看涨

AIStockmoo 评分

-0.3
分析师共识 1.5
内部交易活动 -4.0
价格波动 -3.0
技术平均移动指标 0.0
技术振荡指标 4.0
平均 -0.30

相关股票

股票 市值 DY P/E(TTM) P/B
IONS 13 B - - 21.49
RNA 11 B - - 5.73
ARWR 10 B - - 17.90
NUVL 8 B - - 10.04
SRRK 5 B - - 18.74
AKRO 4 B - - 4.67

Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis received FDA approval in 2024 for Tryngolza for a rare high-triglyceride syndrome, marking its first independent launch.

部门 Healthcare
行业 Biotechnology
投资方式 Small Core
内部持股比例 0.83%
机构持股比例 108.17%

所有权

姓名 日期 持有股份
Tweedy, Browne Co Llc 30 Sep 2025 2,901,216
52周波幅
23.95 (-70%) — 83.61 (2%)
目标价格波幅
65.00 (-20%) — 110.00 (34%)
110.00 (HC Wainwright & Co., 34.67%) 购买
89.50 (9.57%)
65.00 (Goldman Sachs, -20.42%) 保留
平均值 86.64 (6.07%)
总计 12 购买, 2 保留
平均价格@调整类型 70.40
公司 日期 目标价格 调整类型 价格@调整类型
HC Wainwright & Co. 10 Nov 2025 110.00 (34.67%) 购买 69.54
30 Oct 2025 100.00 (22.43%) 购买 74.17
Piper Sandler 04 Nov 2025 77.00 (-5.73%) 购买 72.88
Barclays 30 Oct 2025 95.00 (16.31%) 购买 74.17
23 Sep 2025 80.00 (-2.06%) 购买 62.57
Morgan Stanley 30 Oct 2025 94.00 (15.08%) 购买 74.17
16 Oct 2025 90.00 (10.19%) 购买 73.07
Needham 30 Oct 2025 90.00 (10.19%) 购买 74.17
08 Oct 2025 78.00 (-4.51%) 购买 69.96
RBC Capital 30 Oct 2025 82.00 (0.39%) 购买 74.17
Raymond James 30 Oct 2025 89.00 (8.96%) 购买 74.17
TD Cowen 30 Oct 2025 99.00 (21.20%) 购买 74.17
JP Morgan 08 Oct 2025 80.00 (-2.06%) 购买 69.96
Oppenheimer 08 Oct 2025 90.00 (10.19%) 购买 69.96
Stifel 06 Oct 2025 67.00 (-17.97%) 保留 69.02
Goldman Sachs 26 Sep 2025 65.00 (-20.42%) 保留 64.09
B of A Securities 23 Sep 2025 83.00 (1.62%) 购买 62.57
Guggenheim 23 Sep 2025 92.00 (12.63%) 购买 62.57
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名称 平均购买 ($) 平均卖出 ($) 总净额 总净值 ($)
WENDER JOSEPH H - 81.99 -28,000 -2,295,720
累积净数量 -28,000
累积净值 ($) -2,295,720
累积平均购买 ($) -
累积平均卖出 ($) 81.99
名称 持有人 日期 类型 数量 价格 价值 ($)
WENDER JOSEPH H 董事 01 Dec 2025 自动卖出 (-) 28,000 81.99 2,295,720
日期 类型 细节
02 Dec 2025 公告 Ionis receives U.S. FDA Breakthrough Therapy designation for zilganersen for Alexander disease (AxD)
01 Dec 2025 公告 Ionis receives U.S. FDA Breakthrough Therapy designation for olezarsen for severe hypertriglyceridemia (sHTG)
14 Nov 2025 公告 DAWNZERA™ (donidalorsen) receives positive opinion from CHMP, recommended for approval in EU for hereditary angioedema (HAE)
13 Nov 2025 公告 Ionis Prices Convertible Notes Offering to Refinance 2026 Convertible Notes
12 Nov 2025 公告 Ionis to present at upcoming investor conferences
11 Nov 2025 公告 Ionis Announces Proposed Convertible Offering to Refinance 2026 Convertible Notes
08 Nov 2025 公告 Groundbreaking pivotal study results of olezarsen for severe hypertriglyceridemia (sHTG) presented as a late breaker at AHA Scientific Sessions
06 Nov 2025 公告 Ionis presents new data demonstrating long-term disease control with DAWNZERA™ (donidalorsen) at ACAAI 2025 Annual Meeting
29 Oct 2025 公告 Ionis reports third quarter 2025 financial results and highlights progress on key programs
27 Oct 2025 公告 Detailed data from the landmark CORE and CORE2 pivotal studies of olezarsen for sHTG to be presented as a late breaker at AHA Scientific Sessions
23 Oct 2025 公告 Ionis ranked #2 Top Employer by Science magazine, recognizing industry-leading scientific innovation and company culture
21 Oct 2025 公告 Ionis CEO Brett P. Monia receives 2025 Lifetime Achievement Award from the Oligonucleotide Therapeutics Society
16 Oct 2025 公告 Ionis to hold third quarter 2025 financial results webcast
07 Oct 2025 公告 Ionis showcases transformational medicines and industry-leading pipeline at Innovation Day
22 Sep 2025 公告 Ionis announces positive topline results from pivotal study of zilganersen in Alexander disease
19 Sep 2025 公告 TRYNGOLZA® (olezarsen) approved in the European Union for familial chylomicronemia syndrome (FCS)
12 Sep 2025 公告 Ionis expands Surf Away+ event, marking 10 years of creating unique adaptive experiences for people with neurological diseases
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